US Healthcare Professionals

Doses delivered to your door

Doses delivered to your door

Evrysdi®️ (risdiplam) patients with caretakers

Your shipment is delivered directly to your door and will contain an ~1-month* supply of Evrysdi

Each package within the shipment includes:

*The exact amount you receive is based on your dose and how much your insurance plan allows to be delivered at one time.

Your healthcare provider will determine the right dose for you based on age and weight. Always take the dose exactly as prescribed. Please read the full Patient Information and Instructions for Use that come with your prescription and discuss with your healthcare provider before taking the first dose.
Your healthcare provider will determine the right dose for you based on age and weight. Always take the dose exactly as prescribed. Please read the full Patient Information and Instructions for Use that come with your prescription and discuss with your healthcare provider before taking the first dose.
Explore how to take Evrysdi

Tips to keep in mind

Evrysdi®️ (risdiplam) dose time

Take your medication at approximately the same time each day after a meal or breastfeeding.

  • Evrysdi cannot be mixed with formula or milk
  • Evrysdi must be taken within 5 minutes of when it is drawn up into the syringe
  • If you miss a planned dose, and 6 hours or less have passed, take Evrysdi as soon as possible, and then resume your regular dosing schedule the next day. If 6 hours or more have passed, skip that dose and just resume your regular dosing schedule the next day
     
Patients should drink water after taking Evrysdi®️ (risdiplam)

Drink water after taking Evrysdi to ensure it has been completely swallowed

  • If you are unable to swallow and have a nasogastric or gastrostomy tube, Evrysdi can be administered via the tube. The tube should be flushed with water after delivering Evrysdi
  • If a dose is not fully swallowed or vomiting occurs after administration, another dose should not be taken to make up for the lost dose; the next dose should be taken the following day at the regularly scheduled time

Before preparing your first dose, please be sure to familiarize yourself with the Patient Information and Instructions for Use that come with your prescription.

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Getting started on Evrysdi

A guide to help you get started with Evrysdi treatment

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Important Safety Information and Indication

What is Evrysdi?

Evrysdi is a prescription medicine used to treat spinal muscular atrophy (SMA) in children and adults.

  • Before taking Evrysdi, tell your healthcare provider about all of your medical conditions, including if you:
    • are pregnant or plan to become pregnant, as Evrysdi may harm your unborn baby. Ask your healthcare provider for advice before taking this medicine
    • are a woman who can become pregnant:
      • Before you start your treatment with Evrysdi, your healthcare provider may test you for pregnancy
      • Talk to your healthcare provider about birth control methods that may be right for you. Use birth control while on treatment and for at least 1 month after stopping Evrysdi
      • Pregnancy Registry. There is a pregnancy registry for women who take Evrysdi during pregnancy. The purpose of this registry is to collect information about the health of the pregnant woman and her baby. If you are pregnant or become pregnant while receiving Evrysdi, tell your healthcare provider right away. Talk to your healthcare provider about registering with the Evrysdi Pregnancy Registry. Your healthcare provider can enroll you in this registry or you can enroll by calling 1-833-760-1098 or visiting www.evrysdipregnancyregistry.com
    • are an adult male. Evrysdi may affect a man’s ability to have children (fertility). Ask a healthcare provider for advice before taking this medicine
    • are breastfeeding or plan to breastfeed. It is not known if Evrysdi passes into breast milk and may harm your baby
  • Tell your healthcare provider about all the medicines you take
  • You should receive Evrysdi from the pharmacy as a liquid. If the medicine in the bottle is a powder, do not use it. Contact your pharmacist for a replacement
  • Avoid getting Evrysdi on your skin or in your eyes. If Evrysdi gets on your skin, wash the area with soap and water. If Evrysdi gets in your eyes, rinse your eyes with water
  • The most common side effects of Evrysdi include:
    • For later-onset SMA:
      • fever
      • diarrhea
      • rash
    • For infantile-onset SMA:            
      • fever
      • diarrhea
      • rash
      • runny nose, sneezing, and sore throat (upper respiratory infection)
      • lung infection (lower respiratory infection)
      • constipation
      • vomiting
      • cough

These are not all of the possible side effects of Evrysdi. For more information on the risk and benefits profile of Evrysdi, ask your healthcare provider or pharmacist.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555.

Please see full Prescribing Information for additional Important Safety Information.

    • Información de prescripción de Evrysdi® (risdiplam). Genentech, Inc.

      Información de prescripción de Evrysdi® (risdiplam). Genentech, Inc.