Introducing NEW Evrysdi tablets*

For illustrative purposes only.

*Evrysdi 5-mg tablets are approved for people aged 2 years and older who weigh at least 44 lb (20 kg). The tablets cannot be taken with feeding tubes.

Learn more about Evrysdi tablets

About Evrysdi tablets

The only oral, non-invasive spinal muscular atrophy (SMA) treatment, now in a tablet

The proven results and safety of the liquid form now come with the flexibility of a tablet.

Why Evrysdi tablets may be the right choice for you

Stored at room temperature

Whether at work or on vacation, you can travel with Evrysdi tablets without the need for a cooler bag

Made to fit your lifestyle

You can choose to swallow the tablet whole with water or as a mixture with non-chlorinated drinking water (eg, filtered water, bottled water)—whichever works best for you

No need for measuring

Each once-daily Evrysdi tablet already contains your dose

68°F to 77°F (20°C to 25°C).

Your experience with SMA might be different from others—that’s why having options in how you choose to take Evrysdi is important. Ask your doctor if Evrysdi tablets are right for you

Two ways to take or give Evrysdi tablets

Evrysdi tablets can be swallowed whole with water

OR

Evrysdi tablets can be taken as a mixture with bottled water

  • Keep room temperature bottled water on hand if you want to prepare Evrysdi as a mixture. Don’t mix it with any other liquid than bottled water*
  • Please read the full Patient Information and Prescribing Information that come with your prescription before taking Evrysdi tablets for the first time
  • Watch the video below to learn more about taking Evrysdi tablets

Learn more about obtaining, storing, and taking Evrysdi tablets

Evrysdi presents: Instructions for an SMA Treatment in Tablet Form. If you are starting treatment with Evrysdi, welcome. You're part of a large community of people who together with our doctors have chosen the only oral, non-invasive treatment option for SMA. Before we get started, I would like to review some Important Safety Information with you. 

Now that we've got that covered, let's get started. Evrysdi comes in liquid and five milligram tablet form. They are both strawberry flavored. This video covers the steps involved for taking the tablet only. Evrysdi is delivered directly to your door each month. A specialty pharmacy will work with you to schedule a delivery. The package you receive includes a bottle that holds a 30-day supply of your medication. Check the expiration date and the product for damage before use. Do not use the treatment if it is expired or damaged. When taking the tablet, you just need to take one per day to help treat SMA. Evrysdi tablets can be stored at room temperature, so you have more freedom how and where you take them. It's important to keep the tablets in the bottle you receive them in. Evrysdi tablets are sensitive to moisture and the bottle they arrive in is designed to keep them dry. Remember to tightly secure the cab after each use. There are two ways to take Evrysdi tablets, let's get into those steps. You can swallow the tablet whole with water, or as a liquid, by mixing it in one teaspoon of room temperature bottled water. The tablet mixture cannot be taken using a gastrostomy or nasogastric tube. Press down and twist the cap to open the bottle. Once open, remove one tablet from the bottle. If swallowing the tablet whole, use water to take your dose. Do not take Evrysdi with any other liquid besides water. H2O is the way to go. If mixing the tablet, the liquid you should be using is room temperature bottled water. Tap water has different chlorine levels than bottled water and is not recommended. You'll also need a small, clean empty cup to get started. Pour one teaspoon or five milliliters of room temperature bottled water into your cup. Next, add a tablet and gently swirl the mixture in the cup. This can take up to three minutes. It's normal for the solution to look a little cloudy. Remember to keep the Evrysdi mixture out of sunlight. Drink the mixture right away, if it sits longer than 10 minutes, you'll need to throw it out and start over. To make sure you're also taking any leftover medication in the cup, add one more splash of room temp bottled water, at least one tablespoon or 15 milliliters. Gently swirl the cup once more and drink the remaining mixture right away. Now you're ready to make Evrysdi part of your routine, just like me. My name is Jim. I'm a father and professional voice-over artist and I've been taking Evrysdi since 2020. Now just a few important notes before we say goodbye. These are important people, focus up.

Your doctor, pharmacist, or nurse will show you how to prepare and take Evrysdi tablets. Always take Evrysdi tablets exactly as your healthcare provider tells you. Do not take or give this medicine until you have been shown how to properly prepare and take or give Evrysdi. Do not take an extra dose if you vomit at any time after taking Evrysdi. Store Evrysdi tablets at room temperature, 68°F to 77°F (20°C to 25°C). Do not take or give Evrysdi if it has been exposed to temperatures above 86°F (30°C). Keep the bottle tightly closed in order to protect from moisture. Keep Evrysdi and all medications out of the sight and reach of children. Do not get the Evrysdi tablet mixture on your skin or in your eyes. If the Evrysdi tablet mixture gets on your skin, wash the area with soap and water. If the mixture gets in your eyes rinse your eyes with water. If you spill the Evrysdi tablet mixture, dry the area with a dry paper towel and then clean with soap and water. Throw away the paper towel in the trash and wash your hands with soap and water. If you miss a dose, take it as soon as possible, but no more than six hours after the usual dosing time. If six hours have passed, just wait until the regularly scheduled time the next day. If you have questions about proper disposal, please visit the FDA drug disposal website.

Looking for some additional help? Evrysdi partnership and access liaisons are here. We call them PALs for short and that's fitting because they've got your back on treatment questions and more. Your PAL can help you explore financial support, plan for travel with Evrysdi and point you in the right direction if you're not sure who to call, and connect you to useful resources. If you haven't connected with a PAL yet, you can find the name and contact information for your local PAL at Evrysdi.com/PAL.

Storing Evrysdi: Flexibility that fits your lifestyle

No need to plan your day around treatment. Whether you’re at home or on the go, you can store Evrysdi tablets wherever it’s convenient for you, such as in a cabinet or in your bag.

  • Evrysdi tablets should be kept at room temperature, 68°F to 77°F (20°C to 25°C)
  • The tablets are sensitive to moisture, so don’t transfer them to a pill organizer. Keep them in the bottle they came in and remember to close it tightly

Frequently asked questions

Click on the questions below to learn more about Evrysdi tablets

Evrysdi tablets can either be swallowed whole with water or as a mixture in 1 teaspoon (5 mL) of room temperature bottled water. They cannot be chewed, crushed, cut, or dissolved on the tongue.

Your ability to switch between formulations will depend on discussions with both your healthcare and insurance providers. Be sure to ask your healthcare provider which option is best for you.

Evrysdi tablets are 6.6 mm (0.25 inches) in diameter and 4.1 mm (0.15 inches) in height—about the size of a kernel of corn.

No, unfortunately it cannot be administered via a gastrostomy tube (G-tube) or nasogastric tube (NG-tube). If you or the person you are caring for has a G-tube or NG-tube, you can ask your healthcare provider about taking the Evrysdi liquid.

If you have concerns about costs or insurance coverage, our PALs (Partnership and Access Liaisons) are here to help. You can visit Evrysdi.com/PAL to learn more and connect with a PAL. Reach out anytime.

Evrysdi tablets are only available through a specialty pharmacy. Once prescribed, they will be shipped directly to your door.

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Could Evrysdi tablets be right for you?

Download a printable selection of this information to discuss with your doctor.

Important Safety Information and Indication

What is Evrysdi?

Evrysdi is a prescription medicine used to treat spinal muscular atrophy (SMA) in children and adults.

  • Before taking Evrysdi, tell your healthcare provider about all of your medical conditions, including if you:
    • are pregnant or plan to become pregnant, as Evrysdi may harm your unborn baby. Ask your healthcare provider for advice before taking this medicine
    • are a woman who can become pregnant:
      • Before you start your treatment with Evrysdi, your healthcare provider may test you for pregnancy
      • Talk to your healthcare provider about birth control methods that may be right for you. Use birth control while on treatment and for at least 1 month after stopping Evrysdi
      • Pregnancy Registry. There is a pregnancy registry for women who take Evrysdi during pregnancy. The purpose of this registry is to collect information about the health of the pregnant woman and her baby. If you are pregnant or become pregnant while receiving Evrysdi, tell your healthcare provider right away. Talk to your healthcare provider about registering with the Evrysdi Pregnancy Registry. Your healthcare provider can enroll you in this registry or you can enroll by calling 1-833-760-1098 or visiting www.evrysdipregnancyregistry.com.
    • are an adult male. Evrysdi may affect a man’s ability to have children (fertility). Ask a healthcare provider for advice before taking this medicine
    • are breastfeeding or plan to breastfeed. It is not known if Evrysdi passes into breast milk and may harm your baby
  • Tell your healthcare provider about all the medicines you take
  • If you were prescribed Evrysdi for Oral Solution, you should receive Evrysdi from the pharmacy as a liquid. If the medicine in the bottle is a powder, do not use it. Contact your pharmacist for a replacement
  • Avoid getting Evrysdi on your skin or in your eyes. If Evrysdi gets on your skin, wash the area with soap and water. If Evrysdi gets in your eyes, rinse your eyes with water
  • The most common side effects of Evrysdi include:
    • For later-onset SMA:
      • fever
      • diarrhea
      • rash
    • For infantile-onset SMA:            
      • fever
      • diarrhea
      • rash
      • runny nose, sneezing, and sore throat (upper respiratory infection)
      • lung infection (lower respiratory infection)
      • constipation
      • vomiting
      • cough

These are not all of the possible side effects of Evrysdi. For more information on the risk and benefits profile of Evrysdi, ask your healthcare provider or pharmacist.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555.

Please see full Prescribing Information for additional Important Safety Information.

    • Información de prescripción de Evrysdi® (risdiplam). Genentech, Inc.

      Información de prescripción de Evrysdi® (risdiplam). Genentech, Inc.